EPO-derived 11-AA tissue-protective peptide

Ara-290 (Cibinetide).

An 11-amino-acid synthetic peptide derived from the helix B surface of erythropoietin (EPO). Engineered to bind the EPOR/CD131 heteromer without haematopoietic activity.

Key Information

CompoundARA290
Research categoryRegenerative Research
Available sizes10mg, 16mg
PricingFrom £35
FormatLyophilised powder in sealed vial
Purity>99% by HPLC (Janoshik Analytical, batch-verified)
Intended useIn-vitro laboratory research only. Not for human consumption.

Chemical & Reference Data

Reference data drawn from public databases (PubChem, UniProt) and peer-reviewed literature. For research and laboratory characterisation only.

Compound classSynthetic 11-amino-acid linear peptide derived from EPO helix B (Cibinetide)
Molecular formulaC51H82N16O20
Molecular weight1257.4 g/mol
CAS Registry Number1239358-86-1
Number of residues11
Amino acid sequenceQEQLERALNSS
Receptor / mechanismInnate Repair Receptor (EPO-βcR heteromer) agonist; non-erythropoietic.
Reported half-lifeReported ~2 minutes in human serum (very short).
SolubilityLyophilised powder reconstitutes in bacteriostatic water for laboratory use.
Storage (lyophilised)Stable at 2–8 °C lyophilised for 24+ months.
Storage (reconstituted)Reconstituted: store at 2–8 °C, use within 14 days.
Clinical / regulatory statusPhase 2 in published research.

Research Profile

  • 11-amino-acid EPO-derived peptide
  • Non-haematopoietic EPO analogue
  • Studied in tissue-repair models
  • Third-party purity tested
  • Research use only

ARA290 (Cibinetide) is a synthetic 11-amino-acid peptide derived from the B-helix of erythropoietin. Characterised in the literature for its binding to the innate repair receptor complex (EPOR/βcR) without haematopoietic activity. Supplied as lyophilised powder for in-vitro research use only.

The above describes how this compound is characterised in the published peer-reviewed literature. It is not a claim about effects in humans.

Laboratory Handling

ARA290 is supplied as a lyophilised (freeze-dried) powder in a sealed glass vial. For laboratory reconstitution, add the desired volume of diluent (typically bacteriostatic water) slowly down the side wall of the vial. Swirl gently until fully dissolved - do not vortex or shake. Store reconstituted solutions at 2–8 °C and use within 4–6 weeks.

Use our Reconstitution Volume Calculator to compute the resulting mg/ml concentration.

StateTemperatureShelf life
Lyophilised2–8 °C or −20 °CUp to 24 months
Reconstituted2–8 °C4–6 weeks typical

Purity & Verification

Every batch of ARA290 we supply is independently HPLC-verified by Janoshik Analytical. Where a Janoshik report has been issued for the current batch it is supplied with the order and carries a unique verification key that can be authenticated against Janoshik's records. Reported purity is consistently above 99%.

Related Compounds

Researchers working with ARA290 often work alongside the following compounds in the preclinical literature: