Endogenous tripeptide thiol antioxidant

Glutathione.

An endogenous tripeptide and the principal low-molecular-weight thiol antioxidant in mammalian cells. Reference standard for redox-biology research.

Key Information

CompoundGlutathione
Research categoryLongevity Research
Available sizes600mg, 1500mg
PricingFrom £25
FormatLyophilised powder in sealed vial
Purity>99% by HPLC (Janoshik Analytical, batch-verified)
Intended useIn-vitro laboratory research only. Not for human consumption.

Chemical & Reference Data

Reference data drawn from public databases (PubChem, UniProt) and peer-reviewed literature. For research and laboratory characterisation only.

Compound classTripeptide antioxidant (γ-Glu-Cys-Gly)
Molecular formulaC10H17N3O6S
Molecular weight307.32 g/mol
CAS Registry Number70-18-8
PubChem CID745
Number of residues3
Amino acid sequenceγ-Glu-Cys-Gly (reduced form)
Receptor / mechanismMajor intracellular antioxidant / thiol redox buffer.
Reported half-lifeReported very short serum half-life; intracellular pool dynamics studied widely.
SolubilityLyophilised powder reconstitutes in bacteriostatic water for laboratory use.
Storage (lyophilised)Stable at 2–8 °C lyophilised. Light-sensitive - store in amber vial.
Storage (reconstituted)Reconstituted: store at 2–8 °C, use within 7 days. Oxidises rapidly in solution.
Clinical / regulatory statusEndogenous metabolite; widely used in research.

Research Profile

  • Endogenous tripeptide antioxidant
  • γ-Glu-Cys-Gly sequence
  • Principal intracellular thiol
  • Third-party purity tested
  • Research use only

Glutathione is an endogenous tripeptide (γ-L-glutamyl-L-cysteinyl-glycine) characterised in the biochemical literature as the principal intracellular thiol antioxidant. Supplied as lyophilised powder for in-vitro research use only.

The above describes how this compound is characterised in the published peer-reviewed literature. It is not a claim about effects in humans.

Laboratory Handling

Glutathione is supplied as a lyophilised (freeze-dried) powder in a sealed glass vial. For laboratory reconstitution, add the desired volume of diluent (typically bacteriostatic water) slowly down the side wall of the vial. Swirl gently until fully dissolved - do not vortex or shake. Store reconstituted solutions at 2–8 °C and use within 4–6 weeks.

Use our Reconstitution Volume Calculator to compute the resulting mg/ml concentration.

StateTemperatureShelf life
Lyophilised2–8 °C or −20 °CUp to 24 months
Reconstituted2–8 °C4–6 weeks typical

Purity & Verification

Every batch of Glutathione we supply is independently HPLC-verified by Janoshik Analytical. Where a Janoshik report has been issued for the current batch it is supplied with the order and carries a unique verification key that can be authenticated against Janoshik's records. Reported purity is consistently above 99%.

Related Compounds

Researchers working with Glutathione often work alongside the following compounds in the preclinical literature: