NNMT inhibitor (small molecule)
A small-molecule selective inhibitor of nicotinamide N-methyltransferase (NNMT). Studied alongside peptide GLP-1 agonists in metabolic-research models.
| Compound | 5-Amino-1MQ |
| Research category | Metabolic Research |
| Available sizes | 5mg, 10mg, 50mg |
| Pricing | From £30 |
| Format | Lyophilised powder in sealed vial |
| Purity | >99% by HPLC (Janoshik Analytical, batch-verified) |
| Intended use | In-vitro laboratory research only. Not for human consumption. |
Reference data drawn from public databases (PubChem, UniProt) and peer-reviewed literature. For research and laboratory characterisation only.
| Compound class | Small-molecule NNMT inhibitor (5-amino-1-methylquinolinium) |
| Molecular formula | C10H11N2+ |
| Molecular weight | 159.21 g/mol (cation) |
| CAS Registry Number | 1979-92-2 |
| PubChem CID | 16219527 |
| Receptor / mechanism | Selective NNMT (nicotinamide N-methyltransferase) inhibitor. |
| Reported half-life | Reported short serum half-life in published preclinical literature. |
| Solubility | Lyophilised powder reconstitutes in bacteriostatic water or DMSO for laboratory use. |
| Storage (lyophilised) | Stable at 2–8 °C lyophilised for 18+ months. |
| Storage (reconstituted) | Reconstituted: store at 2–8 °C, use within 14 days. |
| Clinical / regulatory status | Preclinical / investigational. |
5-Amino-1-methylquinolinium (5-Amino-1MQ) is a small-molecule research compound characterised in preclinical literature as a selective inhibitor of nicotinamide N-methyltransferase (NNMT). Supplied for in-vitro research use only.
The above describes how this compound is characterised in the published peer-reviewed literature. It is not a claim about effects in humans.
5-Amino-1MQ is supplied as a lyophilised (freeze-dried) powder in a sealed glass vial. For laboratory reconstitution, add the desired volume of diluent (typically bacteriostatic water) slowly down the side wall of the vial. Swirl gently until fully dissolved - do not vortex or shake. Store reconstituted solutions at 2–8 °C and use within 4–6 weeks.
Use our Reconstitution Volume Calculator to compute the resulting mg/ml concentration.
| State | Temperature | Shelf life |
|---|---|---|
| Lyophilised | 2–8 °C or −20 °C | Up to 24 months |
| Reconstituted | 2–8 °C | 4–6 weeks typical |
Every batch of 5-Amino-1MQ we supply is independently HPLC-verified by Janoshik Analytical. Where a Janoshik report has been issued for the current batch it is supplied with the order and carries a unique verification key that can be authenticated against Janoshik's records. Reported purity is consistently above 99%.
Researchers working with 5-Amino-1MQ often work alongside the following compounds in the preclinical literature: