ActRIIB-Fc fusion protein
A recombinant fusion protein consisting of the extracellular domain of ActRIIB linked to a human IgG Fc region. Activin / myostatin pathway antagonist.
| Compound | ACE-031 |
| Research category | Other Research |
| Available sizes | 1mg |
| Pricing | From £45 |
| Format | Lyophilised powder in sealed vial |
| Purity | >99% by HPLC (Janoshik Analytical, batch-verified) |
| Intended use | In-vitro laboratory research only. Not for human consumption. |
Reference data drawn from public databases (PubChem, UniProt) and peer-reviewed literature. For research and laboratory characterisation only.
| Compound class | Recombinant Activin Receptor Type IIB (ActRIIB) Fc fusion protein |
| Molecular formula | Recombinant Fc-fusion |
| Molecular weight | ~80 kDa |
| CAS Registry Number | TBD |
| Amino acid sequence | Soluble extracellular domain of human ActRIIB fused to human IgG1 Fc. |
| Receptor / mechanism | Soluble myostatin / activin ligand trap. |
| Reported half-life | Reported ~10–15 days in human serum. |
| Solubility | Lyophilised powder reconstitutes in bacteriostatic water for laboratory use. |
| Storage (lyophilised) | Stable at 2–8 °C lyophilised for 12+ months. |
| Storage (reconstituted) | Reconstituted: store at 2–8 °C, use within 14 days. |
| Clinical / regulatory status | Investigational; clinical development discontinued. |
ACE-031 is a soluble form of the activin type IIB receptor (ActRIIB-Fc fusion protein) characterised in preclinical literature for its role in myostatin-signalling pathway research. Supplied as lyophilised powder for in-vitro research use only.
The above describes how this compound is characterised in the published peer-reviewed literature. It is not a claim about effects in humans.
ACE-031 is supplied as a lyophilised (freeze-dried) powder in a sealed glass vial. For laboratory reconstitution, add the desired volume of diluent (typically bacteriostatic water) slowly down the side wall of the vial. Swirl gently until fully dissolved - do not vortex or shake. Store reconstituted solutions at 2–8 °C and use within 4–6 weeks.
Use our Reconstitution Volume Calculator to compute the resulting mg/ml concentration.
| State | Temperature | Shelf life |
|---|---|---|
| Lyophilised | 2–8 °C or −20 °C | Up to 24 months |
| Reconstituted | 2–8 °C | 4–6 weeks typical |
Every batch of ACE-031 we supply is independently HPLC-verified by Janoshik Analytical. Where a Janoshik report has been issued for the current batch it is supplied with the order and carries a unique verification key that can be authenticated against Janoshik's records. Reported purity is consistently above 99%.
Researchers working with ACE-031 often work alongside the following compounds in the preclinical literature: