Modified GHRH 1-29 analogue

CJC-1295 (without DAC).

The same modified GHRH backbone as CJC-1295 (DAC) but lacking the albumin-binding maleimide. ~30 minute serum half-life.

Key Information

CompoundCJC 1295 (without DAC)
Research categoryGHRH / Secretagogue Research
Available sizes2mg, 5mg, 10mg
PricingFrom £25
FormatLyophilised powder in sealed vial
Purity>99% by HPLC (Janoshik Analytical, batch-verified)
Intended useIn-vitro laboratory research only. Not for human consumption.

Chemical & Reference Data

Reference data drawn from public databases (PubChem, UniProt) and peer-reviewed literature. For research and laboratory characterisation only.

Compound classSynthetic GHRH analogue (Modified GRF 1-29) without DAC modification
Molecular formulaC152H252N44O42
Molecular weight3367.9 g/mol
CAS Registry Number863288-34-0
Number of residues29
Amino acid sequenceYADAIFTNSYRKVLGQLSARKLLQDIMSR-NH2 with D-Ala²-Gln⁸-Ala¹⁵-Leu²⁷ substitutions.
Receptor / mechanismGHRH receptor agonist (modified GHRH 1-29).
Reported half-lifeReported ~30 minutes in human serum.
SolubilityLyophilised powder reconstitutes in bacteriostatic water for laboratory use.
Storage (lyophilised)Stable at 2–8 °C lyophilised for 24+ months.
Storage (reconstituted)Reconstituted: store at 2–8 °C, use within 14 days.
Clinical / regulatory statusInvestigational research compound.

Research Profile

  • Mod GRF 1-29
  • Stabilised GHRH analogue
  • Four amino-acid substitutions
  • Third-party purity tested
  • Research use only

CJC 1295 without DAC, also known in the literature as Mod GRF 1-29, is a synthetic GHRH analogue comprising the first 29 amino acids of GHRH with four amino-acid substitutions for stability. Supplied as lyophilised powder for in-vitro research use only.

The above describes how this compound is characterised in the published peer-reviewed literature. It is not a claim about effects in humans.

Laboratory Handling

CJC 1295 (without DAC) is supplied as a lyophilised (freeze-dried) powder in a sealed glass vial. For laboratory reconstitution, add the desired volume of diluent (typically bacteriostatic water) slowly down the side wall of the vial. Swirl gently until fully dissolved - do not vortex or shake. Store reconstituted solutions at 2–8 °C and use within 4–6 weeks.

Use our Reconstitution Volume Calculator to compute the resulting mg/ml concentration.

StateTemperatureShelf life
Lyophilised2–8 °C or −20 °CUp to 24 months
Reconstituted2–8 °C4–6 weeks typical

Purity & Verification

Every batch of CJC 1295 (without DAC) we supply is independently HPLC-verified by Janoshik Analytical. Where a Janoshik report has been issued for the current batch it is supplied with the order and carries a unique verification key that can be authenticated against Janoshik's records. Reported purity is consistently above 99%.

Related Compounds

Researchers working with CJC 1295 (without DAC) often work alongside the following compounds in the preclinical literature:

Compare CJC 1295 (without DAC) with Related Compounds