Research category
UK supplier of nine compounds spanning the GHRH receptor agonists, ghrelin-mimetic GH secretagogues, the GH peptide itself, and IGF-1 analogues. From the canonical GHRH(1-29) reference Sermorelin to the long-acting CJC 1295 with DAC and the selective ghrelin-mimetic Ipamorelin. Every batch independently HPLC-verified by Janoshik Analytical at 99%+ purity. Research use only - not for human consumption.
The "GH-axis" research family splits cleanly into two pharmacological classes that are often studied together:
The two classes act on distinct receptors but converge on the same downstream output: pulsatile GH release. Research literature commonly studies them in combination ("GHRH + GHS") because the two pulses synergise.
The category also includes the GH peptide itself (HGH/Somatropin, 191 AA recombinant) and the long-arg-3 IGF-1 analogue (IGF-1 LR3) for downstream-axis research.
| Compound | Class | Half-life (literature) | Receptor |
|---|---|---|---|
| Sermorelin | GHRH(1-29) native fragment | ~10–20 min | GHRH-R |
| CJC 1295 (DAC) | Modified GHRH + albumin binding | ~6–8 days | GHRH-R |
| CJC 1295 (no DAC) | Modified GRF 1-29 | ~30 min | GHRH-R |
| Tesamorelin | GHRH(1-44) + hexenoyl modification | ~25–40 min | GHRH-R |
| Ipamorelin | Selective ghrelin-mimetic pentapeptide | ~2 hr | GHS-R |
| GHRP-2 | Ghrelin-mimetic hexapeptide | ~15–60 min | GHS-R |
| GHRP-6 | Ghrelin-mimetic hexapeptide | ~15–60 min | GHS-R |
| HGH (Somatropin) | Recombinant 191-AA GH | ~2–4 hr | GH-R |
| IGF-1 LR3 | Long Arg³ IGF-1 analogue | ~20–30 hr | IGF-1R |
The GHRH-R class is unified by sequence homology to native GHRH(1-29). The four compounds in our catalogue differ primarily in pharmacokinetic profile:
Direct comparisons:
The GHS class acts on a different receptor (GHS-R / ghrelin receptor) but produces a synergistic downstream GH pulse. Our three compounds:
Direct comparisons:
HGH (Somatropin) is the recombinant 191-amino-acid human growth hormone. The downstream effector that GHRH and GHS compounds stimulate. Used in research as the direct GH-receptor reference.
IGF-1 LR3 is a long-arg-3 analogue of insulin-like growth factor 1, with a 13-residue N-terminal extension and Arg³ substitution that reduces IGFBP binding. Reference for IGF-1 receptor research with extended pharmacokinetic profile.
Sermorelin is the canonical reference. Use long-acting analogues (CJC 1295 DAC, Tesamorelin) for sustained-stimulation studies.
Ipamorelin for selective ghrelin-mimetic research; GHRP-2 or GHRP-6 for less-selective comparator work.
Common protocols pair Sermorelin or CJC 1295 (no DAC) with Ipamorelin to study synergistic GH-pulse research signals.
HGH (Somatropin) for GH-R studies; IGF-1 LR3 for IGF-1R research with extended half-life.
All compounds in this category are supplied as lyophilised powder in sealed glass vials. Reconstitute with bacteriostatic water added slowly down the side wall, swirling gently. Use the on-site Reconstitution Volume Calculator for mg/mL maths.
Compounds in this category are independently HPLC-verified by Janoshik Analytical at 99%+ purity. Where a Janoshik report has been issued for the current batch it is supplied with the order, and verification records are published on the Purity page.