Mitochondrial-derived peptide
A 16-amino-acid mitochondrial-derived peptide encoded within the 12S rRNA region of mitochondrial DNA. AMPK-mediated metabolic-research compound.
| Compound | MOTS-c |
| Research category | Longevity Research |
| Available sizes | 10mg, 15mg, 20mg, 30mg, 40mg |
| Pricing | From £30 |
| Format | Lyophilised powder in sealed vial |
| Purity | >99% by HPLC (Janoshik Analytical, batch-verified) |
| Intended use | In-vitro laboratory research only. Not for human consumption. |
Reference data drawn from public databases (PubChem, UniProt) and peer-reviewed literature. For research and laboratory characterisation only.
| Compound class | Synthetic 16-amino-acid mitochondrial-derived peptide |
| Molecular formula | C100H167N27O22S |
| Molecular weight | 2174.6 g/mol |
| CAS Registry Number | 1627580-64-6 |
| Number of residues | 16 |
| Amino acid sequence | MRWQEMGYIFYPRKLR |
| Receptor / mechanism | Mitochondrial-derived peptide; AMPK modulator in literature. |
| Reported half-life | Reported short serum half-life in published preclinical literature. |
| Solubility | Lyophilised powder reconstitutes in bacteriostatic water for laboratory use. |
| Storage (lyophilised) | Stable at 2–8 °C lyophilised for 18+ months. |
| Storage (reconstituted) | Reconstituted: store at 2–8 °C, use within 14 days. |
| Clinical / regulatory status | Preclinical / investigational. |
MOTS-c is a 16-amino-acid mitochondrial-derived peptide encoded within the 12S rRNA of mitochondrial DNA. Characterised in the literature for its effects on AMPK signalling and glucose metabolism in cellular and preclinical models. Supplied as lyophilised powder for in-vitro research use only.
The above describes how this compound is characterised in the published peer-reviewed literature. It is not a claim about effects in humans.
MOTS-c is supplied as a lyophilised (freeze-dried) powder in a sealed glass vial. For laboratory reconstitution, add the desired volume of diluent (typically bacteriostatic water) slowly down the side wall of the vial. Swirl gently until fully dissolved - do not vortex or shake. Store reconstituted solutions at 2–8 °C and use within 4–6 weeks.
Use our Reconstitution Volume Calculator to compute the resulting mg/ml concentration.
| State | Temperature | Shelf life |
|---|---|---|
| Lyophilised | 2–8 °C or −20 °C | Up to 24 months |
| Reconstituted | 2–8 °C | 4–6 weeks typical |
Every batch of MOTS-c we supply is independently HPLC-verified by Janoshik Analytical. Where a Janoshik report has been issued for the current batch it is supplied with the order and carries a unique verification key that can be authenticated against Janoshik's records. Reported purity is consistently above 99%.
Researchers working with MOTS-c often work alongside the following compounds in the preclinical literature:
References are independent peer-reviewed sources. Black & White Peptides Ltd is not affiliated with these publications.