Cyclic 7-AA α-MSH analogue
A 7-amino-acid cyclic synthetic analogue of alpha-MSH with a lactam bridge. Broad melanocortin receptor agonism.
| Compound | Melanotan 2 (MT-2) |
| Research category | Melanocortin Research |
| Available sizes | 10mg |
| Pricing | From £30 |
| Format | Lyophilised powder in sealed vial |
| Purity | >99% by HPLC (Janoshik Analytical, batch-verified) |
| Intended use | In-vitro laboratory research only. Not for human consumption. |
Reference data drawn from public databases (PubChem, UniProt) and peer-reviewed literature. For research and laboratory characterisation only.
| Compound class | Synthetic 7-amino-acid cyclic α-MSH analogue (Melanotan II) |
| Molecular formula | C50H69N15O9 |
| Molecular weight | 1024.18 g/mol |
| CAS Registry Number | 121062-08-6 |
| PubChem CID | 92432 |
| Number of residues | 7 |
| Amino acid sequence | Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2 |
| Receptor / mechanism | Non-selective melanocortin receptor agonist (MC1R, MC3R, MC4R, MC5R). |
| Reported half-life | Reported ~30 minutes in human serum. |
| Solubility | Lyophilised powder reconstitutes in bacteriostatic water for laboratory use. |
| Storage (lyophilised) | Stable at 2–8 °C lyophilised for 24+ months. |
| Storage (reconstituted) | Reconstituted: store at 2–8 °C, use within 14 days. |
| Clinical / regulatory status | Investigational research compound. |
Melanotan-2 is a synthetic cyclic heptapeptide analogue of α-MSH characterised in the literature as a non-selective melanocortin receptor agonist with activity at MC1R, MC3R, MC4R and MC5R. Supplied as lyophilised powder for in-vitro research use only.
The above describes how this compound is characterised in the published peer-reviewed literature. It is not a claim about effects in humans.
Melanotan 2 (MT-2) is supplied as a lyophilised (freeze-dried) powder in a sealed glass vial. For laboratory reconstitution, add the desired volume of diluent (typically bacteriostatic water) slowly down the side wall of the vial. Swirl gently until fully dissolved - do not vortex or shake. Store reconstituted solutions at 2–8 °C and use within 4–6 weeks.
Use our Reconstitution Volume Calculator to compute the resulting mg/ml concentration.
| State | Temperature | Shelf life |
|---|---|---|
| Lyophilised | 2–8 °C or −20 °C | Up to 24 months |
| Reconstituted | 2–8 °C | 4–6 weeks typical |
Every batch of Melanotan 2 (MT-2) we supply is independently HPLC-verified by Janoshik Analytical. Where a Janoshik report has been issued for the current batch it is supplied with the order and carries a unique verification key that can be authenticated against Janoshik's records. Reported purity is consistently above 99%.
Researchers working with Melanotan 2 (MT-2) often work alongside the following compounds in the preclinical literature: