7-AA ACTH(4-10) analogue

Semax.

A 7-amino-acid synthetic peptide derived from the ACTH(4-10) fragment with a C-terminal Pro-Gly-Pro for enzymatic stability.

Key Information

CompoundSemax
Research categoryNeuropeptide Research
Available sizes5mg, 10mg
PricingFrom £20
FormatLyophilised powder in sealed vial
Purity>99% by HPLC (Janoshik Analytical, batch-verified)
Intended useIn-vitro laboratory research only. Not for human consumption.

Chemical & Reference Data

Reference data drawn from public databases (PubChem, UniProt) and peer-reviewed literature. For research and laboratory characterisation only.

Compound classSynthetic 7-amino-acid analogue of ACTH(4-10)
Molecular formulaC37H51N9O10S
Molecular weight813.93 g/mol
CAS Registry Number80714-61-0
PubChem CID11765634
Number of residues7
Amino acid sequenceMet-Glu-His-Phe-Pro-Gly-Pro
Receptor / mechanismModulator of melanocortin / BDNF expression pathways in literature.
Reported half-lifeReported short serum half-life; intranasal route discussed in literature.
SolubilityLyophilised powder reconstitutes in bacteriostatic water for laboratory use.
Storage (lyophilised)Stable at 2–8 °C lyophilised for 24+ months.
Storage (reconstituted)Reconstituted: store at 2–8 °C, use within 14 days.
Clinical / regulatory statusApproved in Russia / CIS countries; investigational in research literature elsewhere.

Research Profile

  • Synthetic heptapeptide
  • ACTH (4-7) + PGP extension
  • Studied in BDNF expression models
  • Third-party purity tested
  • Research use only

Semax is a synthetic heptapeptide derived from the N-terminal fragment of adrenocorticotropic hormone (ACTH 4-7) with a C-terminal Pro-Gly-Pro extension. Characterised in preclinical literature for its stability profile and effects on BDNF expression in rodent models. Supplied as lyophilised powder for in-vitro research use only.

The above describes how this compound is characterised in the published peer-reviewed literature. It is not a claim about effects in humans.

Laboratory Handling

Semax is supplied as a lyophilised (freeze-dried) powder in a sealed glass vial. For laboratory reconstitution, add the desired volume of diluent (typically bacteriostatic water) slowly down the side wall of the vial. Swirl gently until fully dissolved - do not vortex or shake. Store reconstituted solutions at 2–8 °C and use within 4–6 weeks.

Use our Reconstitution Volume Calculator to compute the resulting mg/ml concentration.

StateTemperatureShelf life
Lyophilised2–8 °C or −20 °CUp to 24 months
Reconstituted2–8 °C4–6 weeks typical

Purity & Verification

Every batch of Semax we supply is independently HPLC-verified by Janoshik Analytical. Where a Janoshik report has been issued for the current batch it is supplied with the order and carries a unique verification key that can be authenticated against Janoshik's records. Reported purity is consistently above 99%.

Related Compounds

Researchers working with Semax often work alongside the following compounds in the preclinical literature:

  • Selank - Neuropeptide Research
  • Adamax - Neuropeptide Research

Compare Semax with Related Compounds