N-acylated GHRH(1-44) analogue
A 44-amino-acid GHRH analogue with a trans-3-hexenoyl moiety attached to the N-terminus for enhanced enzymatic stability.
| Compound | Tesamorelin |
| Research category | GHRH / Secretagogue Research |
| Available sizes | 2mg, 5mg, 10mg, 20mg |
| Pricing | From £38 |
| Format | Lyophilised powder in sealed vial & pre-reconstituted pen |
| Purity | >99% by HPLC (Janoshik Analytical, batch-verified) |
| Intended use | In-vitro laboratory research only. Not for human consumption. |
Reference data drawn from public databases (PubChem, UniProt) and peer-reviewed literature. For research and laboratory characterisation only.
| Compound class | Synthetic GHRH(1-44) analogue with N-terminal hexenoyl modification |
| Molecular formula | C221H366N72O67S |
| Molecular weight | 5135.9 g/mol |
| CAS Registry Number | 218949-48-5 |
| PubChem CID | 16133824 |
| Number of residues | 44 |
| Amino acid sequence | trans-3-hexenoyl-YADAIFTNSYRKVLGQLSARKLLQDIMSRQQGESNQERGARARL-NH2 |
| Receptor / mechanism | GHRH receptor agonist (1-44 fragment). |
| Reported half-life | Reported ~25–40 minutes in human serum. |
| Solubility | Lyophilised powder reconstitutes in bacteriostatic water for laboratory use. |
| Storage (lyophilised) | Stable at 2–8 °C lyophilised for 24+ months. |
| Storage (reconstituted) | Reconstituted: store at 2–8 °C, use within 14 days. |
| Clinical / regulatory status | Approved by FDA (2010) for HIV-associated lipodystrophy research applications. |
Tesamorelin is a synthetic GHRH analogue comprising the 44-amino-acid GHRH sequence with an N-terminal trans-3-hexenoyl modification. Supplied as lyophilised powder for in-vitro research use only.
The above describes how this compound is characterised in the published peer-reviewed literature. It is not a claim about effects in humans.
Tesamorelin is supplied as a lyophilised (freeze-dried) powder in a sealed glass vial. For laboratory reconstitution, add the desired volume of diluent (typically bacteriostatic water) slowly down the side wall of the vial. Swirl gently until fully dissolved - do not vortex or shake. Store reconstituted solutions at 2–8 °C and use within 4–6 weeks.
Use our Reconstitution Volume Calculator to compute the resulting mg/ml concentration.
| State | Temperature | Shelf life |
|---|---|---|
| Lyophilised | 2–8 °C or −20 °C | Up to 24 months |
| Reconstituted | 2–8 °C | 4–6 weeks typical |
Every batch of Tesamorelin we supply is independently HPLC-verified by Janoshik Analytical. Where a Janoshik report has been issued for the current batch it is supplied with the order and carries a unique verification key that can be authenticated against Janoshik's records. Reported purity is consistently above 99%.
Researchers working with Tesamorelin often work alongside the following compounds in the preclinical literature:
References are independent peer-reviewed sources. Black & White Peptides Ltd is not affiliated with these publications.