Acetylated 28-AA thymic peptide

Thymosin Alpha-1.

A 28-amino-acid acetylated peptide derived from the prothymosin alpha precursor. Widely cited in immunomodulatory research.

Key Information

CompoundThymosin Alpha-1
Research categoryRegenerative Research
Available sizes5mg, 10mg
PricingFrom £25
FormatLyophilised powder in sealed vial
Purity>99% by HPLC (Janoshik Analytical, batch-verified)
Intended useIn-vitro laboratory research only. Not for human consumption.

Chemical & Reference Data

Reference data drawn from public databases (PubChem, UniProt) and peer-reviewed literature. For research and laboratory characterisation only.

Compound classSynthetic 28-amino-acid acetylated peptide derived from thymic prothymosin
Molecular formulaC129H215N33O55
Molecular weight3108.3 g/mol
CAS Registry Number62304-98-7
PubChem CID16130571
Number of residues28
Amino acid sequenceAc-SDAAVDTSSEITTKDLKEKKEVVEEAEN
Receptor / mechanismTLR-9 / immune-modulating peptide profile in literature.
Reported half-lifeReported ~2 hours in human serum.
SolubilityLyophilised powder reconstitutes in bacteriostatic water for laboratory use.
Storage (lyophilised)Stable at 2–8 °C lyophilised for 24+ months.
Storage (reconstituted)Reconstituted: store at 2–8 °C, use within 14 days.
Clinical / regulatory statusApproved (Zadaxin) in several countries for research-relevant immunology indications.

Research Profile

  • 28-amino-acid thymic peptide
  • Fragment of prothymosin alpha
  • Studied in immune-cell signalling models
  • Third-party purity tested
  • Research use only

Thymosin Alpha-1 is a synthetic 28-amino-acid peptide identical to a fragment of the naturally occurring protein prothymosin alpha. Characterised in the literature for its effects on T-cell and dendritic-cell signalling in preclinical models. Supplied as lyophilised powder for in-vitro research use only.

The above describes how this compound is characterised in the published peer-reviewed literature. It is not a claim about effects in humans.

Laboratory Handling

Thymosin Alpha-1 is supplied as a lyophilised (freeze-dried) powder in a sealed glass vial. For laboratory reconstitution, add the desired volume of diluent (typically bacteriostatic water) slowly down the side wall of the vial. Swirl gently until fully dissolved - do not vortex or shake. Store reconstituted solutions at 2–8 °C and use within 4–6 weeks.

Use our Reconstitution Volume Calculator to compute the resulting mg/ml concentration.

StateTemperatureShelf life
Lyophilised2–8 °C or −20 °CUp to 24 months
Reconstituted2–8 °C4–6 weeks typical

Purity & Verification

Every batch of Thymosin Alpha-1 we supply is independently HPLC-verified by Janoshik Analytical. Where a Janoshik report has been issued for the current batch it is supplied with the order and carries a unique verification key that can be authenticated against Janoshik's records. Reported purity is consistently above 99%.

Related Compounds

Researchers working with Thymosin Alpha-1 often work alongside the following compounds in the preclinical literature: