Dual GIP/GLP-1 agonist · LY3298176

Tirzepatide.

A 39-amino-acid acylated peptide with dual activity at GIP and GLP-1 receptors. The most-cited dual incretin reference compound in current metabolic-research literature.

Key Information

CompoundTirzepatide
Research categoryMetabolic Research
Available sizes2mg, 5mg, 10mg, 15mg, 20mg, 30mg, 40mg, 50mg, 60mg, 70mg, 80mg, 90mg, 100mg, 110mg, 120mg
PricingFrom £50
FormatLyophilised powder in sealed vial & pre-reconstituted pen
Purity>99% by HPLC (Janoshik Analytical, batch-verified)
Intended useIn-vitro laboratory research only. Not for human consumption.

Chemical & Reference Data

Reference data drawn from public databases (PubChem, UniProt) and peer-reviewed literature. For research and laboratory characterisation only.

Compound classSynthetic 39-amino-acid dual GIP / GLP-1 receptor agonist peptide
Molecular formulaC225H348N48O68
Molecular weight4813.5 g/mol
CAS Registry Number2023788-19-2
PubChem CID156588324
Number of residues39
Amino acid sequenceYXEGTFTSDYSIYLDKQAAXEFVNWLLAGGPSSGAPPPS-NH2 (X = α-aminoisobutyric acid)
Receptor / mechanismDual agonist: GIP receptor (high affinity) + GLP-1 receptor (high affinity).
Reported half-lifeReported ~120 hours in primate models in the published literature.
SolubilityLyophilised powder reconstitutes in bacteriostatic water for laboratory use.
Storage (lyophilised)Stable at 2–8 °C in lyophilised form for 24+ months.
Storage (reconstituted)Reconstituted: store at 2–8 °C, use within 28 days.
Clinical / regulatory statusApproved by FDA (2022) for type-2 diabetes / obesity research applications.

Research Profile

  • Dual GIP/GLP-1 receptor agonist
  • 39-amino-acid synthetic peptide
  • Lyophilised for laboratory use
  • Third-party purity tested
  • Research use only

Tirzepatide is a synthetic 39-amino-acid peptide characterised in the literature as a dual agonist at the glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors. Supplied as lyophilised powder for in-vitro research use only.

The above describes how this compound is characterised in the published peer-reviewed literature. It is not a claim about effects in humans.

Laboratory Handling

Tirzepatide is supplied as a lyophilised (freeze-dried) powder in a sealed glass vial. For laboratory reconstitution, add the desired volume of diluent (typically bacteriostatic water) slowly down the side wall of the vial. Swirl gently until fully dissolved - do not vortex or shake. Store reconstituted solutions at 2–8 °C and use within 4–6 weeks.

Use our Reconstitution Volume Calculator to compute the resulting mg/ml concentration.

StateTemperatureShelf life
Lyophilised2–8 °C or −20 °CUp to 24 months
Reconstituted2–8 °C4–6 weeks typical

Purity & Verification

Every batch of Tirzepatide we supply is independently HPLC-verified by Janoshik Analytical. Where a Janoshik report has been issued for the current batch it is supplied with the order and carries a unique verification key that can be authenticated against Janoshik's records. Reported purity is consistently above 99%.

Related Compounds

Researchers working with Tirzepatide often work alongside the following compounds in the preclinical literature:

Compare Tirzepatide with Related Compounds

Key Literature References

References are independent peer-reviewed sources. Black & White Peptides Ltd is not affiliated with these publications.