GLP-1 / IgG4-Fc fusion

Dulaglutide.

A long-acting GLP-1 receptor agonist consisting of GLP-1(7-37) analogue molecules linked to a modified human IgG4 Fc fragment.

Key Information

CompoundDulaglutide
Research categoryMetabolic Research
Available sizes5mg, 10mg
PricingFrom £35
FormatLyophilised powder in sealed vial
Purity>99% by HPLC (Janoshik Analytical, batch-verified)
Intended useIn-vitro laboratory research only. Not for human consumption.

Chemical & Reference Data

Reference data drawn from public databases (PubChem, UniProt) and peer-reviewed literature. For research and laboratory characterisation only.

Compound classGLP-1 receptor agonist Fc-fusion protein
Molecular formulaRecombinant Fc-fusion (GLP-1 dimer fused to IgG4 Fc)
Molecular weight~63 kDa
CAS Registry Number923950-08-7
Amino acid sequenceTwo GLP-1 analogue chains linked to a modified human IgG4 Fc fragment.
Receptor / mechanismGLP-1 receptor agonist with extended half-life via Fc fusion.
Reported half-lifeReported ~5 days in human serum.
SolubilityLyophilised powder reconstitutes in bacteriostatic water for laboratory use.
Storage (lyophilised)Stable at 2–8 °C lyophilised for 18+ months.
Storage (reconstituted)Reconstituted: store at 2–8 °C, use within 14 days.
Clinical / regulatory statusApproved by FDA (2014) for research-relevant indications.

Research Profile

  • GLP-1 receptor agonist
  • Fc-fusion protein architecture
  • Extended half-life profile
  • Third-party purity tested
  • Research use only

Dulaglutide is a GLP-1 receptor agonist constructed as an Fc-fusion protein, giving it a larger molecular weight and extended half-life relative to native GLP-1. Supplied as lyophilised powder for in-vitro research use only.

The above describes how this compound is characterised in the published peer-reviewed literature. It is not a claim about effects in humans.

Laboratory Handling

Dulaglutide is supplied as a lyophilised (freeze-dried) powder in a sealed glass vial. For laboratory reconstitution, add the desired volume of diluent (typically bacteriostatic water) slowly down the side wall of the vial. Swirl gently until fully dissolved - do not vortex or shake. Store reconstituted solutions at 2–8 °C and use within 4–6 weeks.

Use our Reconstitution Volume Calculator to compute the resulting mg/ml concentration.

StateTemperatureShelf life
Lyophilised2–8 °C or −20 °CUp to 24 months
Reconstituted2–8 °C4–6 weeks typical

Purity & Verification

Every batch of Dulaglutide we supply is independently HPLC-verified by Janoshik Analytical. Where a Janoshik report has been issued for the current batch it is supplied with the order and carries a unique verification key that can be authenticated against Janoshik's records. Reported purity is consistently above 99%.

Related Compounds

Researchers working with Dulaglutide often work alongside the following compounds in the preclinical literature:

Key Literature References

References are independent peer-reviewed sources. Black & White Peptides Ltd is not affiliated with these publications.