GLP-1 receptor agonist · NN9535
A 31-amino-acid GLP-1 receptor agonist with strong albumin binding via fatty-diacid acylation. The most extensively cited single-target GLP-1 agonist in current research.
| Compound | Semaglutide |
| Research category | Metabolic Research |
| Available sizes | 2mg, 5mg, 10mg, 15mg, 20mg, 30mg |
| Pricing | From £45 |
| Format | Lyophilised powder in sealed vial |
| Purity | >99% by HPLC (Janoshik Analytical, batch-verified) |
| Intended use | In-vitro laboratory research only. Not for human consumption. |
Reference data drawn from public databases (PubChem, UniProt) and peer-reviewed literature. For research and laboratory characterisation only.
| Compound class | Synthetic 31-amino-acid GLP-1 receptor agonist peptide (~94% homology with native GLP-1) |
| Molecular formula | C187H291N45O59 |
| Molecular weight | 4113.58 g/mol |
| CAS Registry Number | 910463-68-2 |
| PubChem CID | 56843331 |
| Number of residues | 31 |
| Amino acid sequence | HXEGTFTSDVSSYLEGQAAKEFIAWLVRGRG (X = α-aminoisobutyric acid; Lys26 acylated with γGlu-2xOEG-C18 diacid) |
| Receptor / mechanism | GLP-1 receptor agonist (single-target). |
| Reported half-life | Reported ~165 hours in human serum in published literature. |
| Solubility | Lyophilised powder reconstitutes in bacteriostatic water for laboratory use. |
| Storage (lyophilised) | Stable at 2–8 °C lyophilised for 24+ months. |
| Storage (reconstituted) | Reconstituted: store at 2–8 °C, use within 28 days. |
| Clinical / regulatory status | Approved by FDA (2017) for research applications in metabolic literature. |
Semaglutide is a 31-amino-acid peptide characterised in the literature as an agonist at the glucagon-like peptide-1 (GLP-1) receptor, sharing approximately 94% sequence homology with native human GLP-1. Supplied as lyophilised powder for in-vitro research use only.
The above describes how this compound is characterised in the published peer-reviewed literature. It is not a claim about effects in humans.
Semaglutide is supplied as a lyophilised (freeze-dried) powder in a sealed glass vial. For laboratory reconstitution, add the desired volume of diluent (typically bacteriostatic water) slowly down the side wall of the vial. Swirl gently until fully dissolved - do not vortex or shake. Store reconstituted solutions at 2–8 °C and use within 4–6 weeks.
Use our Reconstitution Volume Calculator to compute the resulting mg/ml concentration.
| State | Temperature | Shelf life |
|---|---|---|
| Lyophilised | 2–8 °C or −20 °C | Up to 24 months |
| Reconstituted | 2–8 °C | 4–6 weeks typical |
Every batch of Semaglutide we supply is independently HPLC-verified by Janoshik Analytical. Where a Janoshik report has been issued for the current batch it is supplied with the order and carries a unique verification key that can be authenticated against Janoshik's records. Reported purity is consistently above 99%.
Researchers working with Semaglutide often work alongside the following compounds in the preclinical literature:
References are independent peer-reviewed sources. Black & White Peptides Ltd is not affiliated with these publications.